EB jonctionnelle : sous-types

Most common JEB clinical subtypes	Targeted protein(s)
Severe	Laminin 332a
Intermediate	Laminin 332
Intermediate	Type XVII collagen
With pyloric atresia	Integrin α6β4
Localized	Laminin 332, type XVII collagen, integrin α6β4, integrin α3 subunit
Inversa	Laminin 332
Late onset	Type XVII collagen
LOC syndrome	Laminin α3A
With interstitial lung disease and nephrotic syndrome	Integrin α3 subunit

LOC, laryngo–onycho–cutaneous. ^aJEB severe is rarely caused by pathogenic variants affecting the type XVII collagen gene; bold, syndromic JEB subtypes.

Dépliant explicatif "Comme les ailes d'un papillon"

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